El trabajo analiza los aportes que Roig realiza al pensamiento decolonial, a partir de la consideración de tres cuestiones: 1) La “ampliación metodológica” y la consiguiente recuperación de textos propios de la tradición americana que representan una crítica frontal a la filosofía occidental moderna..

En su ensayo Para una crítica de la violencia, Walter Benjamin reivindica el fenómeno social de la huelga general revolucionaria teorizada por Georges Sorel en su obra Reflexiones sobre la violencia, como una figura ejemplar de lo que sería un “medio puro de la política”, al margen de cualquier forma legitimada de poder. En este marco, pocos comentadores contemporáneos advierten una discordancia conceptual entre ambos filósofos: para Sorel, la huelga revolucionaria es un mito social, mientras que el mito, categoría esencialmente (...) negativa en Benjamin, describe la violencia que aprisiona la vida y que se traduce en una forma de poder político superior. En este artículo quisiéramos demostrar esta discordancia conceptual para examinar en seguida cómo ha sido comentada por otros pensadores contemporáneos. La filosofía de la historia, la posibilidad de una acción política ética y la temporalidad mesiánica aparecen en el horizonte teórico que emparenta a estos filósofos y por el cual podría descifrarse su impasse conceptual. Esto se confirma si se despliega la idea de un “medio puro de la política”, pista que Benjamin ofrece sin profundizar y sobre la cual reenvía al pensamiento de un filósofo poco explorado, Erich Unger. En la última parte de este artículo desarrollaremos las claves dadas por Unger, que entran justamente en sintonía con la mención de la huelga general como medio puro de la política. In his Critique of violence, Walter Benjamin claimed that the social phenomenon of the revolutionary general strike was an example of what would be a “pure political mean”. In this context, not many contemporary commentators note an important conceptual incoherence between those two philosophers: for Sorel the revolutionary general strike is a social myth, while in Benjamin the category of myth, essentially negative, describes the violence that imprisons life and crystallizes it in a higher form of political power. In this article, we demonstrate this conceptual discrepancy in order to examine the way it has been approached by other philosophers. The philosophy of history, the possibility of an ethical political action, and messianic temporality, all appear on the theoretical horizon linking these philosophers, and through these ideas a conceptual impasse can be decoded. Moreover, this horizon can be confirmed if we follow the idea of a “pure political means” that Benjamin proposes and which moves forward to the thought of an unexplored philosopher mentioned by him: Erich Unger. In the last part of this article we will develop the keys given by Unger, which fall right in line with the notion of the general strike as a pure political mean. (shrink)

Ante una ciencia mal-tratada desde su interior, un ojo enajenado y confundido en su visión, un ser humano cansado y desconfiado de la misma explicación, un mundo necesitado de comprensión y cuidado, ante unos cuantos insistentes de vivir en unos tiempos y espacios fragmentados, aparece la necesidad de escuchar de nuevo a lo propio, a lo primero y fundante como fuerza de transformación. Así, las siguientes letras reconocen un camino fenomenológico y contemplativo en la gran madre, la Hytcha Guaia, la (...) Pachamama, el primer gran útero, matriz sagrada que alimenta y nutre lo humano en toda su manifestación. Para la psicología, saber de psyque, de alma, su tarea también está en mirarse, recuperarse y a través de un logos trascendente, integrativo, volver a la sensible y sentida escucha de lo divino como curación, por ello su afirmación a lo mágico, chamánico, potente y sagrado del conocimiento telúrico (de tierra), a la medicina que en ella habita y su sanación. La propuesta es el gran camino de andar la tierra, de sentir, escuchar y estar en conciencia de raíz, un camino de cuidado que constata en cada ritual y experiencia la fuerza espiritual de nuestro saber ancestral indígena como primera y perenne ciencia. (shrink)

In this paper we study the axiomatic system proposed by Bourbaki for the Theory of Sets in the Éléments de Mathématique. We begin by examining the role played by the sign \(\uptau \) in the framework of its formal logical theory and then we show that the system of axioms for set theory is equivalent to Zermelo–Fraenkel system with the axiom of choice but without the axiom of foundation. Moreover, we study Grothendieck’s proposal of adding to Bourbaki’s system the axiom (...) of universes for the purpose of considering the theory of categories. In this regard, we make some historical and epistemological remarks that could explain the conservative attitude of the Group. (shrink)

La infracción al deber objetivo de cuidado (IDOC) es una figura introducida en Ecuador en el 2014 con el COIP, con 4 requisitos concurrentes. Para las actuaciones de los Anestesiólogos es necesario evaluar conjuntamente: la ley y reglamento de la especialidad, las normas mínimas de seguridad de la CLASA y los documentos sobre “cirugía segura” de la OMS. Investigamos en este artículo si existe relación entre estas últimas normas y los requisitos mencionados. El objetivo es encontrar la antes mencionada relación (...) y revisar su realidad procesal. Para ello realizamos análisis documental mediante lógica jurídica. Como resultado obtuvimos una correspondencia entre estas normas y los elementos de la IDOC, así como una ausencia de su consideración dentro de las sentencias evaluadas. Se concluye que, si bien son legalmente exigibles, estas normas no son siempre analizadas cuando se juzga una supuesta IDOC, por lo que es necesaria su incorporación al ámbito judicial. (shrink)

Las denuncias por responsabilidad médica en Ecuador se incrementaron en la última década a raíz de la penalización de la mala práctica profesional establecida en el Código Orgánico Integral Penal; la investigación es compleja y el peritaje médico legal se convierte en una pieza fundamental en el conflicto. Aquí analizamos 10 informes periciales de casos de mala práctica médica en Ecuador, se analiza la legislación ecuatoriana y revisión de la literatura referente al tema. Se identificó la falta de protocolos o (...) guías de procedimientos, los informes no cuentan con estructura y es el resultado de la discrecionalidad del perito designado. Se propone un protocolo de actuación pericial que facilitará la actividad del perito y mayor objetividad en la investigación. (shrink)

In this note, the problem of tracking random references and rejecting random perturbations in a quadrotor, both generated by an auxiliary system named exosystem, is solved by extending the deterministic tracking problem to the area of stochastic processes. Besides, it is considered that only a part of the state vector of the quadrotor is available through measurements. As a consequence, the state vector of the plant must be estimated in order to close the control loop. On this basis, a controller (...) to track random references and to reject random perturbations is developed by combining a Kalman filter to estimate the references and perturbations of an exosystem and an observer to estimate the states of a quadrotor. Besides, to obtain a more practical controller, the analysis is carried out in discrete time. Numerical simulations are used in a quadrotor to confirm the validity and effectiveness of the proposed control. (shrink)

Despite abundant evidence associating CD38 overexpression and CD4 T cell depletion in HIV infection, no causal relation has been investigated. To address this issue, a series of mechanisms are proposed, supported by evidence from different fields, by which CD38 overexpression can facilitate CD4 T cell depletion in HIV infection. According to this model, increased catalytic activity of CD38 may reduce CD4 T cells’ cytoplasmic nicotin‐amide adenine dinucleotide (NAD), leading to a chronic Warburg effect. This will reduce mitochondrial function. Simultaneously, CD38's (...) catalytic products ADPR and cADPR may be transported to the cytoplasm, where they can activate calcium channels and increase cytoplasmic Ca2+ concentrations, further altering mitochondrial integrity. These mechanisms will decrease the viability and regenerative capacity of CD4 T cells. These hypotheses can be tested experimentally, and might reveal novel therapeutic targets. (shrink)

El presente artículo busca proponer un acercamiento a la influencia del pensamiento de Thomas Hobbes y su obra en el pensamiento económico. En especial en las escuelas marxista, neoclásica y keynesiana. El influjo de su pensamiento puede evidenciarse en el abordaje metodológico, antropológico e institucional. Se ofrece una Mirada sobre la sociedad civil (comercial), el Mercado y el Estado al mismo tiempo. Hobbes ha sido la inspiración de un concepto de Estado monolítico en lo político, en este sentido, la mirada (...) de la economía bajo el concepto de un gran planificador centralizado, tiene importantes antecedentes en este autor. El ejercicio del control social del individuo como propuesta institucional, en varias escuelas de la economía comparten con Hobbes, varios antecedentes que merecen ser analizados. (shrink)

One of the main tools in the study of nonmonotonic consequence relations is the representation of such relations in terms of preferential models. In this paper we give an unified and simpler framework to obtain such representation theorems.

RESUMEN La neurociencia ha proporcionado valiosas herramientas para analizar problemas filosóficos; sin embargo, el debate sobre el papel de las evidencias neurocientíficas en la explicación de determinados fenómenos mentales sigue abierto. La discusión se centra en la experiencia mística y sus bases neuronales, lo que permite efectuar consideraciones más genéricas acerca de la legitimidad y el alcance de los razonamientos neurocientíficos cuando versan sobre algunos de los más conspicuos productos de la cultura. ABSTRACT Neuroscience has provided valuable tools for the (...) analysis of philosophical problems; however, there is an ongoing debate over the role of neuroscientific evidence in the explanation of certain mental phenomena. The discussion focuses on the mystical experience and its neuronal bases, which makes it possible to carry out more generic considerations regarding the legitimacy and scope of neuroscientific arguments when they involve some of the principal cultural products. (shrink)

The present book verses on the current discussion, between authors writing within the Thomistic tradition, on the issue of human rights, and pretends to adjudicate that discussion. The positions of authors who are critical of the notion of human rights, like Michel Villey and Alasdair MacIntyre, as well as that of those who try to justify their existence and explain their nature, like Jacques Maritain, John Finnis, and others, are carefully explained and evaluated. This book is the first to deal (...) in detail with this contemporary discussion and therefore represents an important contribution to the bibliography on the philosophy of human rights, as well as to the bibliography on the Thomistic tradition. (shrink)

Ante una ciencia mal-tratada desde su interior, un ojo enajenado y confundido en su visión, un ser humano cansado y desconfiado de la misma explicación, un mundo necesitado de comprensión y cuidado, ante unos cuantos insistentes de vivir en unos tiempos y espacios fragmentados, aparece la necesidad de escuchar de nuevo a lo propio, a lo primero y fundante como fuerza de transformación. Así, las siguientes letras reconocen un camino fenomenológico y contemplativo en la Gran Madre, la Hytcha Guaia, la (...) Pachamama, el primer gran útero, matriz sagrada que alimenta y nutre lo humano en toda su manifestación.Para la psicología, saber de psyque, de alma, su tarea también está en mirarse, recuperarse y a través de un logos trascendente, integrativo, volver a la sensible y sentida escucha de lo divino como curación, por ello su afirmación a lo mágico, chamánico, potente y sagrado del conocimiento telúrico (de tierra), a la medicina que en ella habita y su sanación. La propuesta es el gran camino de andar la tierra, de sentir, escuchar y estar en conciencia de raíz, un camino de cuidado que constata en cada ritual y experiencia la fuerza espiritual de nuestro saber ancestral indígena como primera y perenne ciencia. (shrink)

Meeting 5G high bandwidth rates, ultra-low latencies, and high reliabilities requires of network infrastructures that automatically increase/decrease the resources based on their customers’ demand. An autonomous and dynamic management of a 5G network infrastructure represents a challenge, as any solution must account for the radio access network, data plane traffic, wavelength allocation, network slicing, and network functions’ orchestration. Furthermore, federation among administrative domains (ADs) must be considered in the network management. Given the increased dynamicity of 5G networks, artificial intelligence/machine learning (...) (AI/ML) solutions are strong candidates able to learn, and take quick provisioning decisions upon fast changes in network conditions. Therefore, this chapter presents an analysis of the state-of-the-art solutions for 5G networks’ management, where AI/ML solutions are discussed and compared with traditional methods. Additionally, the chapter provides a technology overview of both standards, and existing solutions regarding the 5G network management, and directions toward the integration of AI/ML in 5G networks. (shrink)

The somatic mutation theory (SMT) of cancer has been and remains the prevalent theory attempting to explain how neoplasms arise and progress. This theory proposes that cancer is a clonal, cell‐based disease, and implicitly assumes that quiescence is the default state of cells in multicellular organisms. The SMT has not been rigorously tested, and several lines of evidence raise questions that are not addressed by this theory. Herein, we propose experimental strategies that may validate the SMT. We also call attention (...) to an alternative theory of carcinogenesis, the tissue organization field theory (TOFT), which posits that cancer is a tissue‐based disease and that proliferation is the default state of all cells. Based on epistemological and experimental evidence, we argue that the TOFT compellingly explains carcinogenesis, while placing it within an evolutionarily relevant context.magnified imagemagnified imageAna Soto and Carlos Sonnenschein are at Tufts University School of Medicine, Boston, MA, USA. (shrink)

Are intelligent machines really intelligent? Is the underlying philosoph- ical concept of intelligence satisfactory for describing how the present systems work? Is understanding a necessary and sufficient condition for intelligence? If a machine could understand, should we attribute subjectivity to it? This paper addresses the problem of deciding whether the so-called ”intelligent machines” are capable of understanding, instead of merely processing signs. It deals with the relationship between syntax and semantics. The main thesis concerns the inevitability of semantics for any (...) discussion about the possibility of building conscious machines, condensed into the following two tenets: ”If a machine is capable of understanding (in the strong sense), then it must be capable of combining rules and intuitions”; “If semantics cannot be reduced to syntax, then a machine cannot understand.” Our conclusion states that it is not necessary to attribute understanding to a machine in order to explain its exhibited “intelligent” behavior; a merely syntactic and mechanistic approach to intelligence as a task-solving tool suffices to justify the range of operations that it can display in the current state of technological development. (shrink)

In Ancient Greece, the figure of the hero was identified as a demigod, possessed of altruistic and virtuous deeds. When Pierre de Coubertin reinstated the Olympic Games, the athlete was personified as a modern hero. Its antithesis, the anti-hero, has more virtue that defects, no evil but he does not care on the means to achieve his goals. In the eyes of everyone involved in sports competition, these characters captivate and at the same time, create conflicts of ethics and aesthetics. (...) The purpose of this paper is to perform an ethical reflection linked to principles that contribute for the human growth and accomplishment, as well as the aesthetic on the perception of the sensitive, reverberated by sensations and feelings emerging from athletes. Connecting the ethic with the aesthetic spheres, we could have in the sports a phenomenon walking toward a common point between moral and aesthetic, between the good and the beauty. (shrink)

Cuando ahora las formas de hacer historia materializan una multiplicidad de grafías, y el giro reflexivo y el giro historiográfico nos permiten idear las historias de las teorías de la historia en una posibilidad más, en este ensayo se presenta un deseo, una promesa cuya llave de acceso precisa saber lo que pretende la locución arqueoescritura. Esbozos y trazas de la teoría de la historia en cuestión: ¿qué cabe esperar en las escrituras diferidas de la arqueoescritura? Escrituras equívocas en clave (...) derridiana de la teoría de la historia como historiografía. Una posibilidad imposible aplazada. Escrituras para examinar la metafísica de la presencia en la historiografía, conscientes de que no podrán formular una teoría de la historia en la única firma derridiana, porque lo real se resiste a ser domado e incorporado al impar filosófico derridiano. (shrink)

The somatic mutation theory has been the prevailing paradigm in cancer research for the last 50 years. Its premises are: (1) cancer is derived from a single somatic cell that has accumulated multiple DNA mutations, (2) the default state of cell proliferation in metazoa is quiescence, and (3) cancer is a disease of cell proliferation caused by mutations in genes that control proliferation and the cell cycle. From this compelling simplicity, an increasingly complicated picture has emerged as more than 100 (...) oncogenes and 30 tumor suppressor genes have been identified. To accommodate this complexity, additional ad hoc explanations have been postulated. After a critical review of the data gathered from this perspective, an alternative research program has been proposed. It is based on the tissue organization field theory, the premises of which are that carcinogenesis represents a problem of tissue organization, comparable to organogenesis, and that proliferation is the default state of all cells. The merits of these competing theories are evaluated herein. BioEssays 26:1097–1107, 2004. © 2004 Wiley Periodicals, Inc. (shrink)

The aim of this paper is to analyze the idea of general resurrection of the dead at the end of times in the synoptic Gospels. We intend to clarify whether this concept can be interpreted as a transposition of the parallel belief contained in some intertestamental writings, or if the singularity of the religious experience expressed in the synoptic Gospels establishes an inexorable moment of discontinuity with the previous apocalyptic framework, making it impossible to understand this doctrine on the sole (...) basis of its Jewish precedents. In order to accomplish our goal, we shall first study the general resurrection of the dead in the Q source, the references to this notion in the gospel of Mark, and its meaning in both Matthew and Luke. We will exclude from our treatment all the topics related with the resurrection of Jesus, and we will be focused on the explicit mentions of the doctrine of the resurrection of the dead as such. Since implicit beliefs are always difficult to assess, especially in the context of eschatological ideas, in which vagueness and absence of a systematic effort of exposition often prevail, we will not allude to other synoptic passages which have been regarded as potential expressions of the doctrine of the resurrection of the dead at the end of times. (shrink)

The excessive use of social networks needs to be addressed, and this phenomenon needs to be measured for the purpose of evaluation, prevention, and intervention among adolescents and young people. The objective of the study was to adapt and psychometrically validate the Brief Scale of Addiction to Social Networks among Mexican adolescents and young adults. The participating sample consisted of 2,789 students from 6 public educational campuses in Cuernavaca. Data collection was carried out through a web platform to strictly maintain (...) anonymity, voluntary participation, and confidentiality. Data analysis first focused on the detection of possible response biases, the quality of the response structure partial credit model, dimensionality, and the relationship with external variables. It was found that when the range of efficient response options was limited to less than five, reliability was high, and unidimensionality was maintained. Response biases slightly affected the dimensional structure of the instrument. Measurement invariance reached scalar invariance in the sex, age, and campus groups. The association with sensation seeking and depression, controlling for sex and age covariates, was statistically significant, small, and theoretically consistent. Implications of the results are discussed. (shrink)

Background: Patients at the end-of-life and their families experience a strong emotional impact. The wellbeing of the patient at the end-of-life and their family caregiver are related. Aim: to explore the elements related with the emotional wellbeing of patients with and without cognitive impairment at the end-of-life and that of their primary family caregivers. Design: Cross- sectional study. Participants: data was collected from 202 patients at the end of life with different diagnosis (COPD, cancer and frail elderly) as well as (...) from their respective 202 primary family caregivers. Results: Structural equation models indicated that the emotional state of the patients was best predicted by their functional independence and the burden of their family caregivers. At the same time, the emotional state of the primary family caregiver was predicted by their burden and not by the cognitive state or the functional independence of the patient. Nevertheless, the burden of the family caregiver, which is the only variable predicting both the emotional state of the patient and that of the caregiver, was directly related with the functional independence of the patient and indirectly with the patient’s cognitive state. Conclusions: The burden of the family caregiver stands out as a key factor in the reduction of the emotional distress of patients at the end-of-life –whether or not they present significant cognitive impairment- and that of their family caregivers. (shrink)

The relationship between ethics and performance has previously been addressed in the literature, although there are still some gaps, for example, the relationship of ethical ideologies to student performance. This work aims to contribute to the literature with a statistical evaluation using partial least squares path modelling (PLS-PM) regarding whether university students’ ethical ideologies and moral meaningfulness influence their level of student performance and academic achievement. Results indicate that the ideologies of justice and deontology increase moral meaningfulness, moral meaningfulness in (...) turn increase student’s citizenship behaviours and student’s in-role performance, and finally, student’s in-role performance positively influences academic achievement. This research provides resources applicable to the fields of pedagogy and ethics to encourage performance during the study and highlight the value of the ideologies of justice and deontology. (shrink)

El patrimonio cultural ha adquirido un sentido cada vez más complejo, amplio y dinámico. De una parte, se ha trascendido el antiguo paradigma monumental; de otra, el patrimonio se ha extendido a innumerables ámbitos epistemológicos y prácticos que lo interpretan y aplican según sus intereses.Desde una perspectiva teórica, este trabajo pretende una aproximación conceptual al patrimonio cultural a través de algunas claves que deberían estar presentes en toda reflexión patrimonial. Esta investigación se extenderá también a la noción de Paisaje Urbano (...) Histórico y al ámbito de la arquitectura vernácula a fin de mostrar esa complejidad y su problemática real. (shrink)

El esclarecimiento y la determinación exacta de cuáles pueden haber sido las fuentes, autores o ideas que influyeron decisivamente el pensamiento de Friedrich Nietzsche y el modo como tales referencias teórico-conceptuales pudieron haber quedado incorporadas y expresadas luego en toda la extensión de su obra, constituye uno de los asuntos más complejos y difíciles de abordar para la investigación académica especializada. A materializar dicha tarea indagatoria se dirige este artículo, buscando con ello proveer una estrategia de lectura que permita visualizar (...) focalizadamente ciertos elementos centrales de la reflexión nietzscheana que no siempre son bien reconocidos en la investigación respectiva, cuando no quedan desatendidos por completo en el corpus interpretativo que se ha venido consagrando en relación con su quehacer filosófico. Apoyándose en la investigación especializada, este artículo busca precisar el impacto que pudo haber tenido el pensamiento del filósofo F. A. Lange en Nietzsche; sobre todo reconociendo ciertos elementos de la filosofía crítica de Kant que habiendo sido inicialmente recogidos por Lange, fueron luego heredados como remanentes por Nietzsche, aunque también modificados en su obra, fenómeno que hemos denominado “criticismo radical”. (shrink)

It would be ahistorical to ridicule vitalists. When one reads the writings of one of the leading vitalists like Driesch one is forced to agree with him that many of the basic problems of biology simply cannot be solved by a philosophy as that of Descartes, in which the organism is simply considered a machine…. The logic of the critique of the vitalists was impeccable.At the turn of the new millennium, concomitant with the development of the evo-devo and eco-devo disciplines (...) within developmental biology, critical appraisals of the reductionist stance of the molecular biology revolution became more numerous and noticeable. Several books and papers address the problems posed by this reductionist agenda and suggest... (shrink)

In this paper, we try to expose the fundamental ideas at the basis of Jorge Millas’ axiology. First, we will expose synoptically the core of the legal philosophy that the Chilean thinker develops on his works on the subject, including his conception about philosophy in general , and about legal science in particular . Secondly, we will expose the epistemological suppositions of his legal philosophy , and his consequent conception of law’s essence , the legal rule and its foundation, and (...) the axiological theory that Millas develops on the basis of the distinction and relationship between “is” and “ought” . We conclude with a critical analysis that pretends to expose the strengths and weaknesses of the legal theory of this Chilean author. (shrink)

For the last 50 years the dominant stance in experimental biology has been reductionism in general, and genetic reductionism in particular. Philosophers were the first to realize that the belief that the Mendelian genes were reduced to DNA molecules was questionable. Soon, experimental data confirmed these misgivings. The optimism of molecular biologists, fueled by early success in tackling relatively simple problems has now been tempered by the difficulties encountered when applying the same simple ideas to complex problems. We analyze three (...) examples taken from experimental data that illustrate the shortcomings of this sort of reductionism. In the first, alterations in the expression of a large number of genes coexist with normal phenotypes at supra-cellular levels of organization; in the second, the supposed intrinsic specificity of hormonal signals is negated; in the third, the notion that cancer is a cellular problem caused by mutated genes is challenged by data gathered both from the reductionist viewpoint and the alternative view proposing that carcinogenesis is development gone awry. As an alternative to reductionism, we propose that the organicist view is a good starting point from which to explore these phenomena. However, new theoretical concepts are needed to grapple with the apparent circular causality of complex biological phenomena. (shrink)

This paper examines accounts of the moral wrongness of killing persons in addition to determining what conclusions, if any, can be drawn from the morality of killing persons about the equality of persons, and vice versa. I will argue that a plausible way of thinking about the moral wrongness of killing implies that the permissibility of killing innocent, nonthreatening persons depends on a person’s age. I address objections to this conclusion and discuss some potential implications of the view.